Cytokine-mediated natural killer cells effects impair hematopoietic stem cell function

ChEBI2018-01-02 更新2026-07-12 收录

细胞免疫调节

造血干细胞功能

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-5604 数据链接链接失效反馈

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Cytokine-mediated natural killer cells effects impair hematopoietic stem cell function

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2018-01-02

Vaccine-elicited CD4 T cells prevent the deletion of antiviral B cells in chronic infection

细胞免疫调节

疫苗免疫学

Vaccination induced CD4 T cells prevent B cell decimation by turning on a germinal center like transcriptional program. This cellular differentiation is similiar to the one observed when type I interf

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Vitamin D Regulates Cytokine Patterns Secreted by Dendritic Cells to Promote Differentiation of IL-22-Producing T Cells

细胞免疫调节

T细胞分化

One central mechanism, by which vitamin D regulates human immune responses, is the direct modulation of dendritic cells (DCs). However, the effect of vitamin D on several key DC functions, such as the

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Tumor-Associated Schwann Cell Remodeling under Metabolic Stress via Lactate Sensing Orchestrates

肿瘤微环境代谢

细胞免疫调节

Diabetes mellitus (DM) is a known risk factor for pancreatic cancer, but the underlying mechanisms remain elusive. Using in vivo models of diabetes-driven pancreatic tumorigenesis and metabolomics ana

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Global Gene Expression of hematopoietic stem cells expressing endogenous NrasG12D/G12D, NrasG12D/+, Nras+/+. Mus musculus

造血干细胞功能

肿瘤发生机制

Oncogenic NRAS mutations are frequently identified in human myeloid leukemias. In mice, expression of endogenous oncogenic Nras (NrasG12D/+) in hematopoietic cells leads to expansion of myeloid progen

NIAID Data Ecosystem50

STAT1 is essential for hematopoietic stem cell function and maintains a MHC IIhi stem cell subset that resists myeloablation and neoplastic expansion [LK]

造血干细胞功能

STAT1基因

Adult hematopoietic stem cells (HSCs) are predominantly quiescent and can be activated in response to acute stress such as infection or cytotoxic insults. STAT1 is a pivotal mediator of interferon (I

NIAID Data Ecosystem40

Cytokine-mediated natural killer cells effects impair hematopoietic stem cell function

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