BEN HIV AE Deidentified datasets

For this study, we hypothesized that individuals in the South African population of African descent will have a lower average leucocyte and neutrophil count when compared to a non-African cohort. We also assessed the influence of BEN on the risk for HIV acquisition, as well as its effect on adverse event reporting in a clinical trial. We analysed data from the double-blind, placebo-controlled randomized trial HVTN 503 and its follow-on study HVTN 503-S to assess the prevalence of BEN, its association with HIV infection, and AE reporting. These data were then compared with a time- and age-matched, non-pregnant cohort from the National Health and Nutrition Examination Survey (NHANES) conducted between 2007-2008 in the United States (US). The complete NHANES data are publicly available on the following link: https://wwwn.cdc.gov/nchs/nhanes/Search/DataPage.aspx?Component=Questionnaire&CycleBeginYear=2007 HVTN 503 data will be made available on a website link.