Endothiapepsin crystal B04a from ECBL-96 fragment library screening campaign used for PanDDA ground state calculation Descriptor: Endothiapepsin Authors: Wollenhaupt, J, Benz, L.S, Jirgensons, A, Mile

Protein Data Bank Japan2025-12-31 更新50

Structural studies of protein tyrosine phosphatase beta catalytic domain co-crystallized with a sulfamic acid inhibitor

蛋白质结构解析

药物发现

Structural studies of protein tyrosine phosphatase beta catalytic domain co-crystallized with a sulfamic acid inhibitor Descriptor: CHLORIDE ION, MAGNESIUM ION, N-(TERT-BUTOXYCARBONYL)-L-TYROSYL-N-MET

Protein Data Bank Japan2023-08-30 更新40

table3_QSAR Modeling for Multi-Target Drug Discovery: Designing Simultaneous Inhibitors of Proteins in Diverse Pathogenic Parasites.xlsx

药物发现

多靶点抑制剂

Parasitic diseases remain as unresolved health issues worldwide. While for some parasites the treatments involve drug combinations with serious side effects, for others, chemical therapies are ineffic

NIAID Data Ecosystem60

Anti-cancer activity of the studied compounds (ND—not determined).

抗癌药物

药物发现

Results are expressed as mean ± SD of at least three independent experiments. IC50 values below 10 μM are bolded. Anti-cancer activity of the studied compounds (ND—not determined).

NIAID Data Ecosystem40