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Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor Descriptor: (1S)-2,2-difluoro-1-[1-(pentan-3-yl)-1H-pyrazol-4-yl]ethan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... Authors: Cheung, J, Mahmood, A, Kalathur, R, Lixuan, L, Carlier, P.R. Deposit date: 2017-08-23 Release date: 2018-01-10 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.257 Å) Cite: Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance. Structure, 26, 2018
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2017-08-23
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