DATASET for manuscript "A systems-level multi-omics network approach identifies genetic modifiers in TANGO2 deficiency disorder"

This dataset contains unannotated whole-exome sequencing (VCF) and RNA-Seq (FASTQ, paired-end) data from two siblings with TANGO2 deficiency disorder. TO1 = Subject 1, TO2 = Subject 2. P indicates cell culture passages. Whole-exome sequencing (VCF) SNPs: TANGO2_TO-1.snp.vcf.gz TANGO2_TO-2.snp.vcf.gz Indels: TANGO2_TO-1.indel.vcf.gz TANGO2_TO-2.indel.vcf.gz RNA-Seq (FASTQ)Subject 1 (TO1) Replicate 1 (P6): TO1_20ott21_1.fq.gz, TO1_20ott21_2.fq.gz Replicate 2 (P7): TO1_22ott21_1.fq.gz, TO1_22ott21_2.fq.gz Replicate 3 (P8): TO1_02nov21_1.fq.gz, TO1_02nov21_2.fq.gz Subject 2 (TO2) Replicate 1 (P6): TO2_20ott21_1.fq.gz, TO2_20ott21_2.fq.gz Replicate 2 (P7): TO2_21ott21_1.fq.gz, TO2_21ott21_2.fq.gz Replicate 3 (P8): TO2_02nov21_1.fq.gz, TO2_02nov21_2.fq.gz