Mean scores and 95% CIs according to SARS-CoV-2 infection status and work-related determinants.

# Adjusted for age, sex, marital status and living with children. *Adjusted for age, sex, professional function, marital status and living with children <12 years. During the study follow-up within the larger S3 cohort, we determined (by serologic surveillance and self-reported Nucleic Acid Amplification Tests [NAAT]-results of nasopharyngeal swabs), whether participants were infected with SARS-CoV-2 either prior to receiving vaccination or before the widespread availability of vaccination for all health care workers (HCWs) in the Netherlands (between January and June 2021). In October 2020, participants were surveyed about whether they worked directly in COVID-19 patient care, non-COVID-19 patient care or not working in patient care, as well as the number of years they worked in health care and the number of days per week they worked in the hospital. For those working directly in COVID-19 patient care we noted the amount of work-related exposure to COVID-19 patients, i.e., by estimating the number of times HCW had been in the same room as a COVID-19 (suspected) patient in the previous four weeks (on a scale from none, to 1–5, 6–10, 11–25, 26–50, or more than 50 times), and their primary department of COVID-19 patient care (dedicated COVID-19 nursing ward, emergency department [ED], or intensive care unit [ICU]). Results are reported as mean with 95% confidence interval (CI).
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