Analysis of glioblastoma tissue and corresponding glioblastoma organoids by Exome sequencing. Overall design: Exome sequencing of glioblastoma tumor samples and corresponding glioblastoma organoids
Purpose: More than 90% of children with diffuse intrinsic pontine glioma (DIPG) die within 2 years of diagnosis. There is a dire need to identify therapeutic targets, however lack of patient material
Processed Data accompanying the manuscript: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability Petr Smirn