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Genomic Discovery and Structure-Activity Exploration of a Novel Family of Enzyme-Activated Covalent Cyclin-Dependent Kinase Inhibitors

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NIAID Data Ecosystem2026-05-02 收录
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Phylogenetic sequences and tree files for the publication "Genomic Discovery and Structure-Activity Exploration of a Novel Family of Enzyme-Activated Covalent Cyclin-Dependent Kinase Inhibitors". Figure 2: Phylogenetic comparison of the candidate ros BGC ETaG protein from P. flanaganii with yeast and human CDK protein isoforms. Note that the ETaG is a second copy of and is most closely related to the corresponding housekeeping Pho85. Figure 4: Multiprotein species phylogenetic analysis of 100 fungal housekeeping proteins from 83 fungal strains that were fermented to identify better producers of roseopurpurins. Supplemental Figure 2: Maximum likelihood phylogenetic analysis of concatenated marker genes placed the ros production strain Penicillium sp. (LifeBase accession GN013094.0) in the P. restrictum clade of Penicillium sect. Excilicaulis.
创建时间:
2024-06-19
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