We report the consequences of the disruption of the Fmo5 gene on transcription of genes in liver. Comparison of liver gene expression in wild-type and Fmo5(-/-) mice
Loss-of-function (LoF) mutations associated with disease don’t manifest equally in different individuals, a phenomenon known as incomplete penetrance. The impact of the genetic background on incomplet
Imp2 -/- mice were subjected to a number of characterization assays, including RNA-Seq of various tissues, Overall design: Characterization of IMP2 -/- mice including various metabolic measurements.