Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n Descriptor: 2-{[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methylpiperidin-3-yl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2A Authors: Huang, L.Y, Li, H, Niu, L, Wu, C.Y, Yu, Y.M, Li, L.L, Yang, S.Y. Deposit date: 2019-01-05 Release date: 2019-05-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.598 Å) Cite: Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. J.Med.Chem., 62, 2019
创建时间：
2019-01-05
