Characteristics of the top ranked tunnels of DhaA identified by CAVER 3.0 in molecular dynamics trajectory using the probe radius of 0.9 Å and the clustering threshold of 3.5.

anumber of snapshots in which at least one pathway with bottleneck radius ≥0.9 Å was identified;bnumber of snapshots in which at least one pathway with bottleneck radius ≥1.4 Å was identified;ccharacteristics averaged over identified pathways (i.e. pathways with bottleneck radius ≥0.9 Å), real values will be lower, especially for p1a′, p1b, p2a, p2c and p3 tunnels, which were identified only in a small portion of snapshots.