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Crystal structure of the human METTL3-METTL14 in complex with a bisubstrate analogue (BA6)

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Protein Data Bank Japan2024-11-20 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8pwb
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Crystal structure of the human METTL3-METTL14 in complex with a bisubstrate analogue (BA6) Descriptor: (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(7~{H}-purin-6-ylcarbamoyl)amino]-2-azanyl-butanoic acid, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... Authors: Bedi, R.K, Etheve-Quelquejeu, M, Caflisch, A. Deposit date: 2023-07-19 Release date: 2023-11-08 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The catalytic mechanism of the RNA methyltransferase METTL3. Elife, 12, 2024
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2023-07-19
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