Age-related decline in nuclear envelope LINC complex drives neuronal aging via axon initial segment dysfunction

3M.pc1.bw, 20M.pc1.bw and 20M+Sun1.pc1.bw are BigWig files containing PC1 values obtained from principal component analysis (PCA) of Hi-C data across the genome. These files can be visualized using tools such as the UCSC Genome Browser or IGV.3M.normalized.corrected.cool, 20M.normalized.corrected.cool and 20M+Sun1.normalized.corrected.cool are COOL files containing normalized and corrected Hi-C data. These files are used for the following visualizations:Contact mapfor sample in 3M 20M 20M+Sun1; dohicMergeMatrixBins -m ${sample}.normalized.corrected.cool -o ${sample}.normalized.corrected.nb20.cool -nb 20hicPlotMatrix --matrix ${sample}.normalized.corrected.nb20.cool --outFileName ${sample}.contactmap.png --rotationX 45 --fontsize 6 --log1p --dpi 300doneDistance-dependent contact frequencyhicPlotDistVsCounts --matrices 3M.normalized.corrected.cool 20M.normalized.corrected.cool 20M+Sun1.normalized.corrected.cool --plotFile distvscount.genome.png --labels '3M' '20M' '20M+Sun1'hicPlotDistVsCounts --matrices 3M.normalized.corrected.cool 20M.normalized.corrected.cool 20M+Sun1.normalized.corrected.cool --plotFile distvscount.chromsome.png --labels '3M' '20M' '20M+Sun1' --perchr