Establishment of human teeth relies on coordinated formation of dentin-pulp complex for nurturing and periodontal tissues for anchoring in alveolar bone. The exact cell origin of dentin-pulp complex a

NIAID Data Ecosystem50

Results of all individuals investigated by dental and/or Sr-isotope analysis from Basta.

牙齿发育

同位素生物考古学

The age and sex determination of the individuals are based on international standardized methods [23]. The denotation of the teeth follows the two-digit-system of the World Dental Federation. The inve

Figshare2015-12-02 更新30

Whole lung transcriptome from lung epithelial IRE1a knockout mice

基因敲除转录组

IRE1a功能研究

This experiment sought to characterize the whole lung transcriptional changes induced by loss of IRE1a function in the lung epithelium. Mice were Shh(Cre/+) IRE1a(fl/fl) on the C57BL/6 background, and

NIAID Data Ecosystem60

Arid1a-Plagl1-Hh signaling is indispensable for differentiation-associated cell cycle arrest of tooth root progenitors [ATAC-Seq]. Arid1a-Plagl1-Hh signaling is indispensable for differentiation-associated cell cycle arrest of tooth root progenitors [ATAC-Seq]

分子信号通路

牙齿发育

We show that loss of Arid1a impairs the differentiation-associated cell cycle arrest of tooth root progenitors through Hh signaling regulation, leading to shortened roots. Our data suggest that Plagl1

NIAID Data Ecosystem40

Transcriptional profiling of wild-type vs Perp-null mice during tooth development

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