Supplementary Data: Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading

Data related to the publication "Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading", Parmenter et al., 2024, https://www.biorxiv.org/content/10.1101/2024.08.19.608559v1Full methodology described in the above publication.Total data size = 41 GB<b>Data used for statistical analysis:</b>sCT_DVC_stats_data.csv <i>: Data used for statistical analysis shown in Fig. 3 and Fig. 4</i>DIAD_stats_data.csv <i>: Data used for statistical analysis shown in Fig. 6</i><b>WAXD processing code:</b>processing_folder_D-period.py <i>: python code for measuring diffraction peak parameters</i>ctMapperGUI.py <i>: python code for mapping WAXD parameters onto X-ray projection image</i><br><b>Example sCT and DVC dataset (sample 5):</b>162365_2560xy_2160z_pag100_us2p5_8bit.tif<i> : reconstructed sCT image of sample under 1 N preload, 13 GB, recommend opening in imageJ</i>162366_2560xy_2160z_pag100_us2p5_8bit.tif <i>: reconstructed sCT image of sample after 40 micron displacement, 13 GB, recommend opening in imageJ</i>162365_caudal_mindist4p5_mesh.inp <i>: mesh of caudal VEP used for creating the DVC pointcloud, ABAQUS input file</i>162366_cranial_mindist4p5_mesh.inp <i>: mesh of cranial VEP used for creating the DVC pointcloud, ABAQUS input file</i>162365_caudal_pointcloud.txt <i>: caudal VEP pointcloud for DVC</i>162365_cranial_pointcloud.txt <i>: cranial VEP pointcloud for DVC</i>dvc_162365_caudal.disp <i>: DVC displacement results for caudal VEP, output from iDVC executable, can visualise in Matlab</i>dvc_162365_cranial.disp <i>: DVC displacement results for caudal VEP, </i><i>output from iDVC executable, </i><i>can visualise in Matlab</i>sample5_caudal_step1.csv <i>: strain data for caudal endplate generated from disp file</i>sample5_caudal_step1.csv <i>: strain data for cranial endplate generated from disp file</i>sample5_force_readout.xlsx <i>: force, displacement, time data readout from the mechanical testing rig during the experiment</i>sample5BinaryROIs.zip <i>: binary images of regions used for microarchitecture analysis</i>sample5ROImsvalues.xlsx <i>: microarchitecture values for regions of interest</i><b>Example correlative sCT and WAXD dataset (sample 16):</b>17565_2560xy_2160z_us1_8bit.tif <i>: reconstructed sCT image, 13 GB, recommend opening in imageJ</i>17565_BinaryROI_tifs <i>: binary image regions used for microarchitecture analysis</i>17567 002 dperiod map.png <i>: 002 d-period mapped on X-ray projection</i>17567 002 width map.png <i>: 002 peak width mapped on X-ray projection</i>17567_310_Peak_D-period_data.txt <i>: 310 d-period for each beampath through the sample</i>17567_310_Peak_width_data.txt <i>: 310 peak width for each beampath through the sample</i>17567_D-period_data_002.txt <i>: 002 d-period for each beampath through the sample</i>17567_Width_data_002.txt <i>: 002 peak width for each beampath through the sample</i>k11-17567.nxs <i>: raw diffraction data (part 1)</i><i>, recommend opening in DAWN (both parts required)</i>k11-17567.zip <i>: raw diffraction data (part 2), recommend opening in DAWN </i><i>(both parts required)</i>k11-17567_processed_220722_184414.nxs <i>: processed diffraction data, recommend opening in DAWN</i><br>