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Role of Tubular Cpt1a in Aging Murine Kidneys

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE205497
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To compare the transcriptional profile in aged kidneys lacking tubular Cpt1a with floxed littermate controls. All mice were males and on a mixed background. Kidneys were either from mice that had Cpt1a deleted specifically in renal tubules (crossing Cpt1a floxed mice with Pax8-rTTA;tetO-Cre, which will be called Cpt1aCKO) or floxed controls. They had been treated for 3 weeks with doxycycline to activate Cre at age5-8 weeks.
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2024-03-01
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