Short Stereoselective Synthesis of α-Substituted γ-Lactams
收藏NIAID Data Ecosystem2026-03-06 收录
下载链接：
https://figshare.com/articles/dataset/Short_Stereoselective_Synthesis_of_Substituted_Lactams/3235066
下载链接
链接失效反馈官方服务：
资源简介：
A concise, stereoselective synthesis of α-substituted γ-lactams is reported. γ-Lactam scaffolds 2 and 3, possessing an
Evans' chiral auxiliary and two types of N substituents, were
successfully alkylated with different electrophiles to give
α-substituted γ-lactams with reasonable diastereoselectivities.
The use of a masked carboxymethyl function off the lactam
nitrogen provided a convergent means to α-substituted
γ-lactam dipeptide isosteres.
创建时间：
2016-05-05
