TOP1

ENCODES a protein that exhibits chromatin DNA binding (ortholog); DNA binding (ortholog); DNA binding, bending (ortholog); INVOLVED IN animal organ regeneration (ortholog); cellular response to luteinizing hormone stimulus (ortholog); DNA replication (ortholog); PARTICIPATES IN irinotecan pharmacodynamics pathway; irinotecan pharmacokinetics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); disease of cellular proliferation (ortholog); Disease Progression (ortholog); FOUND IN dense fibrillar component (ortholog); fibrillar center (ortholog)

编码一种具有染色质DNA结合（同源）特性的蛋白质；DNA结合（同源）；DNA结合，弯曲（同源）；参与动物器官再生（同源）；细胞对促黄体生成素刺激的响应（同源）；DNA复制（同源）；参与伊立替康药代动力学途径；伊立替康药效学途径；与自闭症谱系障碍（同源）相关；细胞增殖疾病（同源）；疾病进展（同源）；存在于致密的纤维成分（同源）；纤维中心（同源）