A Unified Approach to the Isomeric α‑, β‑, γ‑, and δ‑Carbolines via their 6,7,8,9-Tetrahydro Counterparts
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https://figshare.com/articles/dataset/A_Unified_Approach_to_the_Isomeric___and_Carbolines_via_their_6_7_8_9-Tetrahydro_Counterparts/4804276
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资源简介:
A cross-coupling/reductive
cyclization protocol has been employed
in a unified approach to all four carbolines. So, for example, the
2-nitropyridine 8, which is readily prepared through
an efficient palladium-catalyzed Ullmann cross-coupling reaction,
is reductively cyclized under conventional conditions to give 6,7,8,9-tetrahydro-α-carboline
that is itself readily aromatized to give α-carboline (1).
创建时间:
2017-03-30



