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Influenza A PB2 (F404Y mutation) in complex with VX-787

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Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
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Influenza A PB2 (F404Y mutation) in complex with VX-787 Descriptor: (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, CHLORIDE ION, Polymerase basic protein 2 Authors: Radilova, K, Brynda, J. Deposit date: 2020-10-26 Release date: 2021-02-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase. Molecules, 26, 2021

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2020-10-26
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