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Crystal structure of the human METTL3-METTL14 complex bound to Compound 2 (ASI_M3M_140)

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of the human METTL3-METTL14 complex bound to Compound 2 (ASI_M3M_140) Descriptor: (2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-~{N}-methyl-3,4-bis(oxidanyl)oxolane-2-carboxamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... Authors: Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. Deposit date: 2019-12-30 Release date: 2020-03-04 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Small-Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer. Chemmedchem, 15, 2020
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2019-12-30
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