Human Protein Atlas - Celltype Atlas

The Single Cell Type Atlas contains single cell RNA sequencing (scRNAseq) data from 13 different human tissues, together with in-house generated immunohistochemically stained tissue sections visualizing the corresponding spatial protein expression patterns. The scRNAseq analysis was based on publicly available genome-wide expression data and comprises all protein-coding genes in 192 individual cell type clusters corresponding to 12 different cell type groups. A specificity and distribution classification was performed to determine the number of genes elevated in these single cell types, and the number of genes detected in one, several or all cell types, respectively. The genes expressed in each of the cell types can be explored in interactive UMAP plots and bar charts, with links to corresponding immunohistochemical stainings in human tissues.

《单细胞类型图谱》收录了来自13个不同人类组织的单细胞RNA测序（scRNAseq）数据，并附带了通过免疫组化染色技术制作的相应空间蛋白表达模式组织切片。该scRNAseq分析基于公开的全基因组表达数据，涵盖了192个个体细胞类型簇中所有蛋白质编码基因，这些簇对应于12个不同的细胞类型组。对特异性及分布进行了分类，以确定在这些单细胞类型中基因上调的数量，以及在一个、几个或所有细胞类型中检测到的基因数量。各细胞类型中表达的基因可以通过交互式的UMAP图和条形图进行探索，并附有链接至人类组织中相应的免疫组化染色切片。