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Transcriptional Activity in Lymph Nodes During the Initiation and Progression of Autoimmune Encephalomyelitis

ChEBI2008-04-03 更新2026-07-21 收录

自身免疫性脑脊髓炎

淋巴结转录组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-7461 数据链接链接失效反馈

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Transcriptional Activity in Lymph Nodes During the Initiation and Progression of Autoimmune Encephalomyelitis

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创建时间：

2008-04-03

神经免疫学

自身免疫性脑脊髓炎

A patient who presented with an encephalopathy, then subsequently developed hiccoughs and extensive myelitis is described. MRI demonstrated an extensive spinal cord and area postrema involvement, and

DataCite Commons2025-06-01 更新80

Preferential use of public T cell receptors during autoimmune encephalomyelitis determined by high resolution saturating sequencing

T细胞受体库

自身免疫性脑脊髓炎

How the TCR repertoire, in concert with risk-associated MHC, imposes susceptibility for autoimmune diseases is incompletely resolved. Due largely to recombinatorial biases, a small fraction of TCR ? o

NIAID Data Ecosystem40

Transplantation of hESC-derived NPs significantly attenuates the clinical severity of EAE.

干细胞治疗

自身免疫性脑脊髓炎

Transplantation of hESC-derived NPs significantly attenuates the clinical severity of EAE.

NIAID Data Ecosystem20

Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions (RNA-Seq I). Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions (RNA-Seq I)

Th17细胞免疫

自身免疫性脑脊髓炎

Pyruvate dehydrogenase (PDH) is the central enzyme connecting glycolysis and the tricarboxylic acid (TCA) cycle. The importance of PDH function in Th17 cells is unknown. Here, we show that PDH is esse

NIAID Data Ecosystem50

Single-cell transcriptional profiling of Th17 cells, differentiated in vitro for 48h [IL1B_IL6_IL23-48h-IL-17A/GFP+]

Th17细胞

自身免疫性脑脊髓炎

Extensive cellular heterogeneity exists within specific immune-cell subtypes classified as a single lineage, but its molecular underpinnings are rarely characterized at a genomic scale. Here, we use s

NIAID Data Ecosystem40

Transcriptional Activity in Lymph Nodes During the Initiation and Progression of Autoimmune Encephalomyelitis

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