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资源简介：
Human innate lymphoid cells: insights into function at homeostasis and during filarial infection.
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创建时间：
2017-11-21
相关数据集
Bulk RNA sequencing of WT and Batf-/- ILC2s sorted from lungs at day 9 after influenza virus infection. Bulk RNA sequencing of WT and Batf-/- ILC2s sorted from lungs at day 9 after influenza virus infection
Activated type 2 innate lymphoid cells (ILC2s) accumulate and promote inflammatory resolution and tissue repair in host defense against acute respiratory viral infections. However, whether an ILC2 sub
NIAID Data Ecosystem80
single cell RNAseq analysis of ILCs from TC-1 tumors
study of Innate lymphoid cells from TC-1 tumors, 1,3 and 7 days after a cisplatin treatment (or PBS as control) Overall design: study of ILCs from PBS or Cisplatin treated TC-1 tumors
NIAID Data Ecosystem60
ST2 Deficiency Does Not Impair Type 2 Immune Responses during Chronic Filarial Infection but Leads to an Increased Microfilaremia Due to an Impaired Splenic Microfilarial Clearance
Background Interactions of the Th2 cytokine IL-33 with its receptor ST2 lead to amplified Type 2 immune responses. As Type 2 immune responses are known to mediate protection against helminth infection
NIAID Data Ecosystem30
Cytotoxic Innate Lymphoid Cells Sense Cancer Cell-Expressed Interleukin-15 to Suppress Human and Murine Malignancies
Malignancy can be suppressed by the immune system. However, the classes of immunosurveillance responses and their mode of tumor sensing remain incompletely understood. Here, we show that while clear c
NIAID Data Ecosystem70
Table_2_c-Rel Is Required for IL-33-Dependent Activation of ILC2s.pdf
Group 2 innate lymphoid cells (ILC2s) are emerging as important cellular regulators of homeostatic and disease-associated immune processes. The cytokine interleukin-33 (IL-33) promotes ILC2-dependent
NIAID Data Ecosystem50
