pEC50 values, fold change in EC50, and difference in basal BRET ratio compared to wild-type for AVP-induced β-arrestin2/Venus recruitment to V2R/Rluc8.
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Transfected HEK293FT or COS7 cells were treated as per Figure 3. Data shown are the pEC50 values for AVP treatment (60 min), fold change from the wild-type EC50, and the BRET ratio for each receptor minus the mean BRET ratio for wild-type receptor (both prior to addition of agonist). Data are the mean ± SEM of 3 independent experiments.*, significantly different to the corresponding wild-type receptor in the same cell line (P
创建时间:
2015-12-02



