Transcriptomic analysis of HOK following interaction with diploid and haploid Candida albicans strains

A comprehensive RNASeq analysis was performed on Primary Human Oral Keratinocytes following their interaction with the haploid WT strain GZY903 and the diploid strain SC5314. Results imply the differential response of host to both strain types. Primary Human Oral Keratinocytes (HOK) were co-cultured with Haploid Wild type strain GZY903 and diploid wild type strain SC5314 at an MOI of 1 for 6 hours. Uninfected HOK were processed in parallel as controls. RNA was extracted from infected and uninfeted cultures for RNA Seq analysis.