Transcriptomic study of NR8383 rat macrophages cells following exposure to NH2-functionalized carbon nanotubes (NRCWE049)

To identify differentially expressed genes and key biological pathways that define toxicity following nanomaterial exposure, we performed microarray analyses on NR8383 macrophages exposed for 4 h to 1.2 cm²/cm² of NH2-functionalized carbon nanotubes (NRCWE049). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement N°. 686098为鉴定纳米材料暴露后诱导毒性的差异表达基因（differentially expressed genes）与关键生物学通路，我们对经1.2 cm²/cm²氨基功能化碳纳米管（NH₂-functionalized carbon nanotubes，NRCWE049）暴露处理4小时的NR8383巨噬细胞开展了基因芯片分析。本项目获欧盟地平线2020（Horizon 2020）研究与创新计划资助，资助协议编号为686098。