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Genome-wide H3K27ac deposition in MCF-7 cells treated with p300 KAT inhibitor A-485

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE172174
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资源简介:
MCF-7 (Estrogen receptor positive breast cancer) cells were treated with p300 KAT inhibitor A-485 and genome wide H3K27ac deposition was measured by ChIP-seq. MCF-7 cells were treated with A-485 (3 µM) for 24 hours. Chromatin was extracted, sonicated, and histones enriched with H3K27ac were immunoprecipitated. Purified DNA was used for library construction and ChIP-sequencing.
创建时间:
2021-07-15
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