Chromosome-level Asian elephant genome assembly and comparative genomics of long-lived mammals reveal the convergent substitutions for cancer resistance. Elephas maximus

The naked mole-rat (Heterocephalus glaber), bats (e.g., gesus Myotis), and elephants (family Elephantidae) are known as long-lived mammals and are assumed to be the excellent cancer antagonists. However, whether there are common genetic changes underpin cancer resistance in these long-lived species is yet to be fully established. Here, we newly generated a high-quality chromosome-level Asian elephant (Elephas maximus) genome.