Note: CpG sites in bold font were found to be significantly associated with callous-unemotional traits The Factor Loadings of each CpG Site onto the Principal Component of Overall HTR1B Methylation.
5-mC is an epigenetic modification of the DNA base cytosine with roles in gene silencing events, imprinting and X inactivation. Phenobarbital (PB) is a well studied non-genotoxic carcinogen with roles
MethylGPT: a foundation model for the DNA methylome Kejun Ying, Jinyeop Song, Haotian Cui, Yikun Zhang, Siyuan Li, Xingyu Chen, Hanna Liu, Alec Eames, Daniel L McCartney, Riccardo E. Marioni, Jesse R
Additional file 4. Augmented EPICv2 manifest. A .csv file containing a new version of the manifest with additional information to aid interpretation and analysis of data.
aall forward primers (top) included the following common sequence at the 5′ end: AGGAAGAGAG; all reverse primers (bottom) the sequence CAGTAATACGACTCACTATAGGGAGAAGGCT.