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Knockdown of PGC-1a suppresses dysplastic oral keratinocyte cells proliferation through reprogramming energy metabolism

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NIAID Data Ecosystem2026-05-01 收录
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To investigate the effects of knockdown PGC1a on human dysplastic oral keratinocyte (DOK) cell proliferation, cell cycle, apoptosis, xenograft tumor, mitochondrial DNA (mtDNA), mitochondrial electron transport chain complexes (ECT), ROS, oxygen consumption rate (OCR), extracellular acidification rate (ECAR), and glucose uptake Overall design: Compared gene expression profiling analysis of RNA-seq data for DOK cells after being infected with PGC1a knockdown or control lentivirus.

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2023-09-14
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