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Transcriptomic analysis during mouse trophoblast stem cell differentiation

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA649558
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This project profiled the transcriptome of undifferentiated Trophoblast Stem Cells (TSCs) and 4-days differentiated Trophoblast Giant Cells (TGCs) cells through RNA-seq and identified ~7,800 differentially expressed genes which include regulators of the cell cycle, apoptosis, cytoskeleton, cell mobility, embryo implantation, metabolism and various signaling pathways. We also identified hitherto undiscovered, cell-type-specific alternative splicing events in 31 genes and expression of 19 novel exons in 12 genes in TSCs and TGCs
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2020-07-29
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