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The structure of human glycinamide ribonucleotide transformylase in complex with 10S-methylthio-DDATHF.

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4ew2
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The structure of human glycinamide ribonucleotide transformylase in complex with 10S-methylthio-DDATHF. Descriptor: N-({4-[(1S)-4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-(methylsulfanyl)butyl]phenyl}carbonyl)-L-glutamic acid, PHOSPHATE ION, SULFATE ION, ... Authors: Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A. Deposit date: 2012-04-26 Release date: 2013-07-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry, 52, 2013
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2012-04-26
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