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Crystal structure of Compound 1 with PIP4K2A

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of Compound 1 with PIP4K2A Descriptor: (2~{R})-2-[[3-cyano-2-[4-(2-ethoxyphenyl)phenyl]-5,8-dihydro-1,7-naphthyridin-4-yl]amino]propanoic acid, PHOSPHATE ION, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Authors: Holton, S.J, Wortmann, L, Braeuer, N, Irlbacher, H, Weiske, J, Lechner, C, Meier, R, Puetter, V, Christ, C, ter Laak, T, Lienau, P, Lesche, R, Nicke, B, Bauser, M, Haegebarth, A, von Nussbaum, F, Mumberg, D, Lemos, C. Deposit date: 2020-04-07 Release date: 2021-04-14 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A. J.Med.Chem., 64, 2021
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2020-04-07
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