Gene expression profiling by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1X knock-down

Gene expression of T47D-MTVL human breast cancer cells expressing Dox-inducible shRNAs against histone H1X (H1Xsh). Overall design: Stable breast cancer-derived cell lines expressing an shRNA against H1X in response to doxycycline (Dox) were grown for six days in the presence or absence of Dox, RNA extracted, and high-throughput sequenced. Cell lines used: inducible shRNA against H1X histone H1 variant.