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Effect of GDF11 on RANKL-induced osteoclastogenesis. Mus musculus

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NIAID Data Ecosystem2026-03-09 收录
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GDF11 treatment leads to bone loss in mice and strongly stimulates RANKL-induced osteoclastogenesis of bone marrow–derived macrophages (BMMs) in vitro. We used microarrays to identified distinct classes of up-regulated genes in BMMs after GDF11 treatment. Overall design: Mouse BMMs were treated with or without GDF11 for RNA extraction and and hybridization on Affymetrix microarrays

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2016-07-20
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