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Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment Descriptor: 5-(4-chlorophenyl)furan-2-carbohydrazide, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... Authors: McIntyre, P.J, Collins, P.M, von Delft, F, Bayliss, R. Deposit date: 2017-08-17 Release date: 2017-11-01 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. ACS Chem. Biol., 12, 2017

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2017-08-17
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