Deciphering responses of the fetal suprachiasmatic nuclei to the rhythmic maternal signals using omics approach

We report circadian (time series, circadian time 0, 3, 6, 9, 12, 18, 21h) transcriptomic analysis of mouse fetal (embryonic day 17) suprachiasmatic nuclei (SCN) from either sham operarated ad libitum fed mothers (group A) or from SCN-lesioned mothers on resctricted feeding regime. The analysis revealed low amplitude rhythms in the fetal SCN driven by maternal SCN and/or maternal feeding behavior.本数据集报道了小鼠胚胎（胚胎第17天）视交叉上核（suprachiasmatic nuclei, SCN）的昼夜节律时间序列转录组分析（transcriptomic analysis），采样的昼夜时间（circadian time）点为0、3、6、9、12、18、21小时。实验分为两组：组A为接受假手术且自由进食的母鼠所产胚胎，另一组为视交叉上核损毁并采用限食方案的母鼠所产胚胎。分析结果显示，胎儿SCN存在低振幅节律，该节律由母鼠SCN和/或母鼠进食行为驱动。