Peripheral T-cell lymphoma (PTCL) represents a rare group of heterogenous diseases in urgent need of effective treatments. A scarcity of disease-relevant preclinical models has considerably hindered r
We have found that thyroid hormones (THs), acting as soluble integrin αvβ3 ligands, activate growth-related signaling pathways in T-cell lymphomas (TCL). Specifically, TH-activated αvβ3 integrin signa
Patients with lymphoma harboring TP63 rearrangements have aggressive clinical course and dismal prognosis with no target therapy available. Thus, there is an urgent need to elucidate the molecular mec
