five

Zebrafish juvenile mpeg+ macrophages

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE149787
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We used zebrafish lacking functional csf1r or il34 to unravel how and when csf1r is necessary for macrophages. Transcriptomic analysis of mpeg+ macrophages isolated from juvenile fish revealed that csf1r deficient macrophages show a gross macrophage transcriptome, but reduced expression of engulfment related genes and increased expression of genes typical for metaphocytes. Bulk RNA sequencing of juvenile macrophages obtained from wildtype control, il34-/- and csf1rDM zebrafish (triplicates)
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2020-05-26
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