A cancer avatar models prospectively guides therapy. A cancer avatar models prospectively guides therapy

Analysis of transcriptomic fidelity between primary and pdx tumor. The hypothesis tested in the present study was that pdx can serve as high fidelity models of human cancer and guide longitudinal care. Results provide important information on the response of preservation of gene expression changes between the primary tumor and the first generation pdx. Overall design: Total RNA obtained from primary and patient derived xenografts (PDX) tumor