Structure of CHK1 10-pt. mutant complex with pyrrolopyrimidine LRRK2 inhibitor

Structure of CHK1 10-pt. mutant complex with pyrrolopyrimidine LRRK2 inhibitor Descriptor: 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile, CHLORIDE ION, Serine/threonine-protein kinase Chk1 Authors: Dokurno, P, Williamson, D.S, Acheson-Dossang, P, Chen, I, Murray, J.B, Shaw, T, Surgenor, A.E. Deposit date: 2017-08-09 Release date: 2017-10-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1). J. Med. Chem., 60, 2017