Additional file 30 of Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant phenotypes

Additional file 30: Table S24. Clusters of TRB clones that are enriched in the repertoire of patients with rheumatoid arthritis and healthy individuals compared to a naive repertoire. Summary statistics of the TRB clusters’ enrichment in the immune repertoire of rheumatoid arthritis patients and healthy controls compared to a naive repertoire of CD4+ and CD8+ T cells (P<0.1). The name of the most representative amino acid motif of each TRB cluster is based on the nomenclature used by the GLIPH2 algorithm. Detailed information on the clones that belong to each TRB cluster is also provided, including the number of unique clones, CDR3 amino acid sequences as well as V and J gene segments. Abbreviations: N, sample size, FDR, false discovery rate.

补充文件30：表S24。相较于初始T细胞库，类风湿关节炎患者与健康个体免疫库中富集的T细胞受体β链（TRB）克隆簇。本表格汇总了相较于CD4+及CD8+初始T细胞库时，TRB克隆簇在类风湿关节炎患者与健康对照者免疫库中的富集统计数据（P<0.1）。每个TRB克隆簇的最具代表性氨基酸基序名称，遵循GLIPH2算法的命名规范。本表格同时提供了各TRB克隆簇所属克隆的详细信息，涵盖独特克隆数量、CDR3氨基酸序列以及V、J基因片段。缩略词说明：N，样本量；FDR，错误发现率（false discovery rate）。