NB literature review with focus on human tissue localization, pathology implication, and methods of culture and detection used for identification of NB.

aDMEM was used in most studies; RPMI-1640 was used in the remaining few.bImmuno-detection: immuno-fluorescence (IF), Western blotting (WB), Ouchterlony immuno-diffusion assay (OI), enzyme-linked immuno-sorbent assay (ELISA), immuno-histochemistry (IH), dot-blotting (DB), and immuno-gold TEM (I-EM).c8D10, 8/0, 5/2, and A4002 are commercial monoclonal antibodies raised against bovine NB (Nanobac Oy). Polyclonal antibodies were also generated against different NB cultures. NM: Not mentioned.