Differentiation of acute myeloid leukemia cells
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA88047
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We developed a general approach to small molecule library screening called GE-HTS (Gene Expression-Based High Throughput Screening) in which a gene expression signature is used as a surrogate for cellular states and applied it to the identification of compounds inducing the differentiation of acute myeloid leukemia cells. In screening 1,739 compounds, we identified 8 that reliably induced the differentiation signature, and furthermore yielded functional evidence of bona fide differentiation. This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
创建时间:
2004-01-30



