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Gene profiles induced by overexpression of wild-type and mutant Notch1 variants in MCF10A mammary epithelial cell line

ChEBI2010-03-23 更新2026-07-21 收录

Notch信号通路功能研究

乳腺癌相关基因表达谱

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-20285 数据链接链接失效反馈

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资源简介：

Gene profiles induced by overexpression of wild-type and mutant Notch1 variants in MCF10A mammary epithelial cell line

应用场景：

创建时间：

2010-03-23

Notch信号通路功能研究

小鼠基因表达分析

BACKGROUND: The Notch signaling pathway is an evolutionary conserved signal transduction pathway involved in embryonic patterning and regulation of cell fates during development and self-renewal. Rece

NIAID Data Ecosystem40

RNA-sequence data of liver sinusoidal endothelial cells in wild type and endothelial RBPj-conditional knock out (RBPjcKO) mice. RNA-sequence data of liver sinusoidal endothelial cells in wild type and endothelial RBPj-conditional knock out (RBPjcKO) mice

内皮细胞转录组

Notch信号通路功能研究

The Notch pathway plays a critical role in regulating the proliferation and differentiation of endothelial cells during liver homeostasis, so we used EC-specific RBPj conditional knock out mice, and c

NIAID Data Ecosystem20

NOTCH dimerization contributes to maintenance of intestinal homeostasis

肠道干细胞调控

Notch信号通路功能研究

A tri-protein complex containing NICD, RBPj and MAMl1 binds DNA as monomer or, cooperatively, as dimers to regulate transcription. Mice expressing Notch dimerization-deficient (DD) alleles Notch1DD an

NIAID Data Ecosystem00

Notch Signaling in the Thyroid is Essential for Adult Homeostasis (RNAseq thyroid)

甲状腺研究

Notch信号通路功能研究

Notch signaling between neighboring cells vitally contributes to specifying their identity and function, during development and in the adult. Here, we demonstrate that selective blockade of the Notch

NIAID Data Ecosystem20

Effect of Notch1 signaling on muscle engraftment and maturation from pluripotent stem cells. Effect of Notch1 signaling on muscle engraftment and maturation from pluripotent stem cells

肌肉干细胞再生

Notch信号通路功能研究

Pluripotent stem cell-derived iPax3 myogenic progenitors display an embryonic molecular signature but become postnatal upon transplantation. Because this correlates with upregulation of Notch signalin

NIAID Data Ecosystem10

Gene profiles induced by overexpression of wild-type and mutant Notch1 variants in MCF10A mammary epithelial cell line

资源简介：

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