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Crystal Structure of the Human p21-Activated Kinase 4 in Complex with PF-03758309

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2x4z
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Crystal Structure of the Human p21-Activated Kinase 4 in Complex with PF-03758309 Descriptor: GLYCEROL, PF-3758309, SERINE/THREONINE-PROTEIN KINASE PAK 4 Authors: Knighton, D.R, Deng, Y, Murray, B, Guo, C, Piraino, J, Westwick, J, Zhang, C, Lamerdin, J, Dagostino, E, Loi, C.-M, Zager, M, Kraynov, E, Christensen, J, Martinez, R, Kephart, S, Marakovits, J, Karlicek, S, Bergqvist, S, Smeal, T. Deposit date: 2010-02-03 Release date: 2010-05-19 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Small-Molecule P21-Activated Kinase Inhibitor Pf- 3758309 is a Potent Inhibitor of Oncogenic Signaling and Tumor Growth. Proc.Natl.Acad.Sci.USA, 107, 2010
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2010-02-03
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