Human Protein Atlas - Cell line

The Cell line resource contains information on genome-wide RNA expression profiles of human protein-coding genes in 1206 human cell lines, including 1132 cancer cell lines. The transcriptomics analysis includes classification based on specificity analysis across 28 cancer types, distribution and expression cluster analysis across all cell lines and for selected cancer types also analysis of similarity of the cell lines to their corresponding cancer type. More information about the specific content and the generation and analysis of the data in the resource can be found in the Methods summary.
Learn about:

if a gene is enriched in cellines from a particular cancer type (specificity)
which genes have a similar expression profile across the cell lines (expression cluster)
the catalogue of genes elevated in each of the cell lines
which cell line has the most consistent expression profile to its corresponding TCGA disease cohort (i.e., the best cell lines for cancer study)
cancer-related pathway and cytokine activity of each cell line

本细胞系资源收录了1206个人类细胞系中蛋白质编码基因的全基因组RNA表达谱信息，其中包含1132个癌细胞系。转录组学分析涵盖了基于28种癌症类型特异性分析的分类、所有细胞系及选定癌症类型的分布和表达聚类分析，以及针对所选癌症类型，细胞系与其对应癌症类型相似性的分析。关于资源中特定内容的详细信息和数据的生成与分析方法，可在方法总结中查阅。了解以下内容：
1. 某一癌症类型细胞系中富集的基因（特异性）；
2. 在细胞系中具有相似表达谱的基因（表达聚类）；
3. 每个细胞系中上调的基因目录；
4. 与其对应的TCGA疾病队列表达谱最一致的细胞系（即最适合癌症研究的最佳细胞系）；
5. 每个细胞系的癌症相关通路和细胞因子活性。