Single cell multi-omic sequencing (CITEseq) of human peripheral blood mononuclear cells (PBMCs)

We utilized CITESeq to investigate changes in immune cell frequencies and their transcriptomic signatures in PBMCs obtained from subjects with low and high coronary artery disease (CAD) severity quantified using gensini scoring system as well as subjects with and without IgE to alpha-gal sensitization We compared changes in immune cell subtypes between subjects with low and high CAD severity or with and without IgE to alpha-gal sensitization Raw data files include reads for both gene expression and antibody-derived tags