Crystal structure of PHGDH in complex with BI-4924
收藏Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of PHGDH in complex with BI-4924 Descriptor: 2-[4-[(1~{S})-1-[[4,5-bis(chloranyl)-1,6-dimethyl-indol-2-yl]carbonylamino]-2-oxidanyl-ethyl]phenyl]sulfonylethanoic acid, D-3-phosphoglycerate dehydrogenase Authors: Bader, G, Wolkerstorfer, B, Zoephel, A. Deposit date: 2019-04-26 Release date: 2019-08-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.984 Å) Cite: Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) InhibitorBI-4924Disrupts Serine Biosynthesis. J.Med.Chem., 62, 2019
创建时间：
2019-04-26
